I have recently been diagnosed as being a
carrier of alports syndrome and I was
wondering if anyone can tell me the
consequences in having children if you are
a carrier. I know that females can pass
it down to males and vice versa and am
concerned that when I have children; if it
is a boy then he will become a carrier
also. Can anyone clarify exactly how
this works in genetics? Is there any way
in which you can prevent this?
i am no expert in this field and clearly
the situation is not a simple one.
However for the bulk of patients the
hereditary pattern is (from a lay point of
view) very much akin to haemophilia i.E
the female is the carrier and only boys
will be affected when they receive the
affected x chromosome from their mother.
Non affected boys will not pass on the
carrier or affected state. Affected boys
can pass their x to daughters who will
then be carriers. Sons of carriers will
have a 50% chance of being affected
depending on which x chromosome they
"inherit". The link describes it much
better! I have probably committed heresy
in the eyes of all geneticists but it
seemed that no-one was replying to the
query.
