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Lucrin depot and endometriosis

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DoctorQuestion
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Lucrin depot and endometriosis
Posted: 05-11-08 05:44am

Dear Dr,



I had a choclate cyst in my left ovary and hydrosalphinx in my left fallopian tube both removed in an operation recently.

As a part of the fertility treatment after 15 days, on the second day of my period i was admininstered 11.25 mg lucrin depot in my right abdomen.

The doctor said my periods will stop for three months after which my harmone levels will stabilise.



However after the injection i have experienced the foll side effects:

excess white discharge from 1st to 3rd day

radiating pain in lower back and upper legs from 4rth to 8th day

blood clots from 7th to 9th day

periods from 9th to 11th day (today)



im baffled as to how i could get periods inspite of such a high dosage.

please urgently inform what could be happening to me



aditi


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DoctorAnswer
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Fertility Answer A4117
Posted: 05-16-08 19:37pm

Lucrin depot is a GnRH-analog that, if given continuously, suppresses production of FSH and LH and then indirectly suppresses estrogen and progesterone production from the ovaries.


Lucrin shuts down the axis hypothalamus-pituitary-ovaries and prevents further ovulations and periods. Now you experience irregular uterine bleeding (metrorrhagia) because the level of estrogen hormones increases shortly and then decreases completely. This is a temporary condition that can last until estrogens reach zero level and endometrial growth becomes completely suppressed.


This procedure is used for treating endometriosis. You might have endometriosis of the removed ovary because a chocolate cyst is caused by ovarian endometriosis.


This procedure with Lucrin is also used to prepare the woman for “in vitro”-fertilization. A woman’s own production of FSH and LH should be stopped before starting stimulation with synthetic FSH and LH from outside.


You should consult your gynecologist about these side effects from Lucrin.





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