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methotrexate side effects

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Aussiegirl

New User, Becoming EHEALTHy
Joined: 23 Jun 2008
Posts: 2
methotrexate side effects
Posted: 06-23-08 20:45pm

I was prescribed Methotrexate (mthoblastin) and salazaphyrin for my RA 4yrs ago. at first the relief was great. I really thought I was on a winer. some time later I started having some real health issues, tired all the time felt like a washed out rag, memory problems, brain felt like it was always in a fog, coordination problems, dizzy lost of balance. Then it got worse developed the shakes couldn't co ordinate brain and motor skills and mild seizures. I was sent to a range of specialists and no definitive answers maybe this maybe that. A couple of months ago I was in absolute joint pain couldn't walk etc totally wiped out I decided that the drugs were not working so I STOOPED TAKING THEM.
Today I can walk I mowed the lawn first time in 3years have a clear head and I am not tired all the time. I can function. My new RA specialist agreed that the drugs sometimes had that effect but still wanted to increase the dosage.
I have some permanent mild symptoms left over with memory. My question is have other people had similar side effects and where any of them permanent. Doctors do persist in prescribing drug on drugs. Not one of my many doctors even thought to look at my medications as a course.
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MandMs

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Joined: 26 Jan 2007
Posts: 2500
Location: , Europe
Thanks: 64
Thanked:16
Hi!
Posted: 06-25-08 12:40pm

Feeling of malaise, undue fatigue, chills and fever, dizziness and decreased resistance to infection are frequently reported side effects of methotraxate.
Headaches, drowsiness, blurred vision, transient blindness, speech impairment, convulsions can, also, occur following administration of methotrexate.
Occasionally, its use can be followed with transient subtle cognitive dysfunction (impaired process of being aware, knowing, thinking, learning and judging) and mood alteration.
Salazopyrin in some patients can cause seizures (convulsions) and balance problems (feeling dizzy).

For how long you are meds free?
How do you feel considering your chronic illness?
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Aussiegirl

New User, Becoming EHEALTHy
Joined: 23 Jun 2008
Posts: 2
methotrexate side effects
Posted: 06-25-08 18:19pm

Thank you M and Ms for your reply. while I was reading it I saw the last miserable 4 years flash by again. I am staying off all RA medication at the moment hoping that the Remission stays awhile although my RH factors are 10 times normal.
I finally feel like I can get my life back I lost my job was but on a disability pension so I have a lot to get back.
what really has me concerned is that none of the doctors or Specialists over the time(all 5) even looked at the possibility that medication could have been responsible. Even know the Doctors are trying to hand out new pills and when I have a say about them they get really annoyed.
Never mind I feel great.
Thank you for your info.
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MandMs

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Joined: 26 Jan 2007
Posts: 2500
Location: , Europe
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Posted: 07-01-08 13:49pm

You are welcome!
I'm happy you are feeling much better.
You can think of using some alternative ways to lessen your pain.
Turmeric, ginger, and botswellia are used for their anti-inflammatory properties.
Acupuncture can be used for pain relief, too.

Best wishes!
Marija
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roxiebabi

New User, Becoming EHEALTHy
Joined: 25 Aug 2008
Posts: 5
methotrexate
Posted: 08-25-08 21:01pm

Hello,
I am currently on methotrexate for my arthritis and have been on and off for the last couple years. I have also noticed some of these side effects. Since i've been on this medication I am fatigued all the time, have slight memory problems, stutter more, feel dizzy/lightheaded, and shakey at times. (I am almost 21 yrs old) I haven't felt like myself in a long time. On top of the arthritis I had lyme disease last year from getting bit by a tick and that may have to do with the side affects too.

I stopped taking methotrexate a couple times when my knees were doing good and not swollen at all but it doesn't last long enough and before you know it the arthritis comes back and I had to go back on it Sad

Well I hope you are doing well, I just wanted to reply because I have found myself to have similar reactions to the methotrexate. Very
Happy
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