27yrs old female, never been pregnant
i have been recently told by my doctor
that I most likely have this disease.
Since then off course I have read one book
" a guide to the polycystic ovary: its
effects on health and fertility" by
professor gabor kovacs &jane smith.
This did clarify some questions I had.
I have now read your info on the matter.
My question is with a partially positive
hx: of transitional amenorrhea, with
menohrragia and dysmenorrheal when my
periods occur. Menarche 14 yrs of age
(never regular).
Also as mentioned in the book their is a
familial tendency for early onset baldness
in men (which is positive on my dad's
side... Men start going bald in their
teens) ( from what I can understand the
abnormality would not be carried on the
sex gene.. And this is how it would
express itself in men).
I was for many yrs of having infrequent
periods.. And on investigation they
discovered a polyp (could having a polyp
be due to the long standing unopposed
estrogen) (i was not on birth control or
any meds for the past 6 yrs or any type of
pill at that)
i was moderately obese as a child but
became slim as a teenager other than the
residual belly that I have never been able
to get rid off (which is typical of
insulin resistance)
now with a partially positive hx, my
question is with a ratio of fsh of 5 iu/l
and lh 19 iu/l (which is typical)
progesterone 1 nmol/l
estradiol-17 beta 143 pmol/l
tsh 1.43 miu/l
prolactine 7 ug/l
but!
This is where I get confused
testosterone 0.6 nmol/l (which is lo)
testosterone-free 4.0 (which is normal)
(note this blood work was taken before any
birth control was initiated)
now from all of my readings I understood
that you would need to have elevated
testosterone.. Which I do not.. But I
do have the positive increased lh fsh
ratio? On top of the hx?
So is this dx correct to polycystic ovary
syndrome with out having elevated
testosterone??
The other question I have is:
is it the hyperinsulimic state that causes
the androgen excess?
So that women with pcos are essentially
insulin resistant.. And the nature of
the disease and the androgen excess is
caused by the carbohydrate resistant state
and or the over insulin production..
Or is it the androgens that cause the
hyperinsulin state????
I hope someone can answer my questions
many thanks!
|
Georgia59
Moderator
Joined: 11 Apr 2007 Posts: 5323 Location: Along the Mississippi, USA
Thanks: 64
Thanked:28
Posted: 03-21-08 21:10pm
Well, I'm not a doc. But from what I found
online, you don't necessarily have to have
a certain level of testosterone, because
PCOS is diagnosed based on a clump of
symptoms, not just one or two tests. Know
what I mean? Are you having any other
symptoms that goes along with that, like
unwanted hair or acne?
Since the actual causes of the disease
remain unknown, it's difficult to
determine exactly what is necessary for
diagnosis. Therefore, if you have enough
symptoms so it seems like you have it, you
can be diagnosed even if it all doesn't
fit perfectly.
Anyway, it also seems to me (from what
I've read) that the insulin problems are
caused by the hormone imbalance. However,
it's all interrelated (all the hormones in
your body are so complexly related that
it's hard to tell what causes what)
That's all I got!
Hope I helped at least a little,
Danielle
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