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Warning: Champix/chantix + Bipolar = Disaster

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purplesage

New User, Becoming EHEALTHy
Joined: 22 Oct 2007
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Warning: Champix/chantix + Bipolar = Disaster
Posted: 10-22-07 06:50am

I'm bipolar and have been taking 200mg Lamictral and 25mg Seroquel for about 2 years now, with some success. Recently I decided to quit smoking and to make it more likely that I'd succeed I started taking a new quit-smoking medicine, known as Champix or Chantix.

After 5-7 days I started having the manic trip of my life, stronger than any I had ever experienced. I spent a month in a state of total euphoria. And this in spite of the fact that my mania normally expresses itself as rage and irritability -- this is only the second classic manic episode I've had in my LIFE (the first was triggered by a SSRI). Jesus was I happy! And since I had virtually no experience with euphoric mania, I was clueless.


Of course, everything came crashing down, and I'm dealing with a brutal depression and more intense suicidal ideation than I can remember ever having. EVER. So be warned, bipolars - avoid Champix / Chantix like the plague. Better to smoke yourselves to death -- you'll probably live far longer that way. (NOTE: Of course this drug is not contraindicated for bipolar - it's new, and drug companies invariably do trials on people who are healthy in every way)
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Jake3463

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Joined: 19 Aug 2007
Posts: 28
Location: Allentown
Ditto
Posted: 10-22-07 11:07am

Same thing happened with me. I'm on Abilify and Lamictal. Started having wierd dreams and than I started to get paranoid and have racing thoughts. I don't think they tested the drug for interactions with bp medications.
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abnrmlmind

Experienced User , Rather EHEALTHy
Joined: 07 Oct 2007
Posts: 55

Posted: 10-22-07 20:05pm

i enjoy euphoric episodes but i tend to make problems for myself. abilify... doctors give that to people that have schitzophrenia also. i dunno what lamictal is, almost sounds like something youd put up your bum. just because champix / chantix did that to you doesnt necessarily mean it will to others, everyone is different.
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Jake3463

New User, Becoming EHEALTHy
Joined: 19 Aug 2007
Posts: 28
Location: Allentown
Mixxing Drugs
Posted: 10-23-07 17:31pm

You mix drugs you might have a reaction. Nothing against Chantix but I doubt the standard round of test they did didn't include people on bipolar medication. Give it time and we'll be on the list of possible interactions.
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Catecholamine

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Joined: 12 Nov 2007
Posts: 2

Posted: 11-13-07 09:25am

Oh, you might do well on a kappa-opioid agonist. It down-regulates acetylcholine receptor mRNA, inhibits the release of both norepinephrine and acetylcholine, and it should have an overall stabilizing effect on your moods. It might also reduce your chances of developing propensities for alcoholism. No promises. I'm just a mad sage. I wouldn't let anyone suffering from bipolar disorder within nine yards of Chantix, though. It would make you kids climb the walls. I don't know why it wasn't immediately contraindicated.

Keep the euphoric trips under control. Whenever I let these things get out of hand, I do an icarus, and daaaaaaaang it hurts when I fall. I discovered a few years ago that, if I can keep the manic episodes in check, I can nearly altogether escape the depression and still stay on a constant life high. It's so great. I don't know if I'm bipolar, though. It's cyclothymia at the very least. Me and my tangents.

The OP is correct. Avoid chantix like the plague. It's wonderful for most people, poison for someone affected with bipolar.
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puzzld

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Posted: 11-20-07 11:01am

i take chantix and a list of other meds, for bipolar, and have no quarrel with it. although, it does make me extremely nauseous if i haven't eaten first. that sucks for you.... i'm trying to quit right now, too, with little success i'm afraid. good luck!
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Catecholamine

New User, Becoming EHEALTHy
Joined: 12 Nov 2007
Posts: 2

Posted: 11-23-07 15:27pm

You're taking it FOR bipolar? Bah, now I'm going to have to revise my conclusions again. Different strokes, different folks, I guess.
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puzzld

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Posted: 11-25-07 19:19pm

ah... no sorry mistyped... thought, brain cloud. NOT taking chantix for bipolar; i'm taking it to assist in my efforts to quit smoking. i probably meant 'in conjunction with' bipolar meds, as discussed on this forum category topic whatever.

as i'm reading this thread again i'm remembering taking chantix while taking seroquel 600mg/day, lamactile 1mg/day, cymbalta 60mg/day and ativan 6mg/day. and i was just, 2 weeks ago, diagnosed with bipolar 1 as a result of who knows what; first manic episode just before a fight with mom to panic attack to full blown hyperventilation. BUT, i don't think taking these meds together has caused my ill temper and terror because i felt this way long before chantix.

it is true... different strokes for different folks

a dr overdosed me on paxil once.

hang in there.... this too will pass.
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pebbles07

New User, Becoming EHEALTHy
Joined: 28 Nov 2007
Posts: 37
Location: ,

Posted: 11-30-07 02:52am

cold turkey is the safest way i think
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