radiation after negative bone scan ? Posted: 02-16-08 18:02pm
this question is by proxy for my father
who had a R.P. 24 months ago.
a radio-oncologist solicited a saturday
call recently and said "to come on in &
we'll zap it into oblivion".[ start feb
.25 th]
wise or unwise?
some internet postings on salvage
radio-therapy are bleak on their
scientific efficacy e.g. 75 % chance of
elevated p.s.a. within 5 years ,overall.
others a much more positive prognosis.[
depends on many variables]
too much info. to correlate for an
amatuer.
dad's original diagnosis was gleason 3+4,
[7] psa =10, dre =negative,
pathologist upgraded diag. to t3c [ s.
vessicules involvement]
note : cancer grew independently at site.
no nodes.
psa 6 weeks after R.P. = .03 , 3 months
thereafter = .03, .05, .05,.09, .083,
.115.[latest]
recent bone scan was negative.
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MandMs
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Posted: 02-19-08 03:55am
Is your father experiencing rising PSA and
cancer recurrence that affects seminal
vesicles?
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mdyar
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Joined: 16 Feb 2008 Posts: 2 Location: ,
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Posted: 02-19-08 18:40pm
yes , psa appears to be on the rise
though at very low levels still.
should be at nadir or nil.
as far as cancer recurrence , being
locally in the prostatic bed or systemic [
distant]at this point ,know one know's or
can know.
but i appears there is definitely a
bio-chemical failure.
i was suspicious of the good doctor's
solicitous phonecall , but i recently had
some help on another forum, saying by his
personal experience with P.C., that time
is of the essence in this scenerio.
he ran the statistics[ dads #'s] thru a
flow chart , and came up with a 50 percent
chance for salvage radio-therapy to work.
heads or tales !
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MandMs
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Joined: 26 Jan 2007 Posts: 1537 Location: Eastern Europe
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Posted: 03-13-08 03:13am
What are his last PSA readings?
Radical prostatectomy, usually, includes
complete removal of both seminal
vesicles.
If there are retained portions of the
seminal vesicle, retained seminal vesicle
tissue may secrete PSA (meticulous removal
of the entire seminal vesicle should be
routine with radical prostatectomy) PSA
levels should be undetectable after
radical prostatectomy. So, for patients
whose PSA levels fail to become
undetectable after radical prostatectomy,
it may be appropriate to consider imaging
before initiating adjuvant therapy such as
radiation.
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