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Medical Questions-> Health Forums -> Lupus -> SLE Systemic Lupus Erithematosus: what treatment can I recei
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DoctorQuestion
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SLE Systemic Lupus Erithematosus: what treatment can I recei
Posted: 10-07-06 15:54pm

I have been dianosed with LUPUS Neuropsychiatric. I have 2 brain leisions on the left side of my brain. I was dianosed with fybromyalgia 10 years ago. In Sept 2004 I contract hepititis from the herpes virus, it statred with a fever blister on my lip and spread without my mouth, nose and sinuses. I have been taking numeriou drugs but have not been able to find any research concusive to Lupus Neuropsychiatric. I was put on PLAQUENIL a year ago. I just want answers on what is best treatment I can recieve. I live in Bakersfield, CA. and there are only 2 Rheumatologist in the area. I can't seem to get my Neuroligists and rheumatologist on the samr page. Weird thing are happening in my bodybut my inflamation count is low. Please help me I need to know what can be done and where to go for help. I'm scared of what will happen next. I have tried to talk to my rheumatolist but I don't think he fully understands Lupus NP. Here is a list of my meds. ESTRADIOL
ZYRTEC
LEXAPRO
NEXXUIM
GABAPENTIN
TRAMADOL
SULAR
LUNESTA
REQUIP
HYDROXYCHLOROQUINE
RESTASIS
BACLOFEN
SEROQUEL
PAIN INJECTIONS TO
A multiple vitamin, folic acid, zinc, B complex daily, an injection of vitamin B every 2 weeks. Caltrate


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DoctorAnswer
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Lupus Answer A1621
Posted: 10-16-06 02:48am

The symptoms you describe (hepatitis, blisters on the lips, mouth, nose, osteo-arthritis, high blood pressure, memory loss, depression) are probably the result of systemic lupus erithematosus (SLE). SLE is an autoimmune disease wherein the immune system creates antibodies against the body's owns structures. Antibodies and antigens together create immune complexes that can be precipitated into various organs: the skin, kidneys, nervous system, joints, muscles, lungs, heart, gastrointestinal tract, eyes, blood cells, etc. Immune complexes cause chronic inflammation in the organs where they are precipitated. Chronic inflammation then causes progressive damage of those organs.
The nervous system can be affected during SLE and manifest as: seizures, extra-pyramidal signs, lesions of the cranial nerves, polyneuritis, and psychiatric symptoms (depression, psychosis etc.).
SLE is treated with corticosteroids, immunomodulators, immunosupressors, and other anti-inflammatory drugs. Therapeutic response to drugs and doses are strictly individual.
Prognosis of this disease depends upon the level of damage to the vital organs and systems (kidneys, heart and brain).
You need an expert opinion from a neurologist and a rheumatologist.



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