Doctors want to help prevent a premature birth but there is very little that can be done when delivery begins. Neither can cercluge help when delivery begins. Further, the benefit of cercluge in preventing premature birth is under question. You didn’t tell me anything about the reasons for your daughter’s last premature delivery. In many cases, the reasons for premature birth remain unknown. Real prevention is taken when doctor and mother can find and treat the reason(s) that may cause premature birth. For instance, a cervical-vaginal infection and inflammation (cervicitis) causes premature maturation of the cervix. The cervix becomes soft, short and the cervical canal starts to extend. This is one example. You might try to identify the cause for repeated premature birth with an OB-GYN or fertility specialist.