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Elevated Ast, Alt, Ggt, Prolactin But Not Alp

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maznass

New User, Becoming EHEALTHy
Joined: 30 Apr 2007
Posts: 1
Location: vancouver
Elevated Ast, Alt, Ggt, Prolactin But Not Alp
Posted: 04-30-07 03:54am

Hi I need advice form a doc or any competent person who has good knowledge of cause of elevated liver enzymes and prolactin. Couple of days ago I decided I take blood work to see if things are normal. I test Hemoglobin, total bilirubin, ALP, AST, ALT, GGT, glucose fasting, HDL, LDL, TSH, Testosterone, Triglyceride, Estradiol, and Prolactin. Every thing came back in range except for Hemoglobin, AST, ALT, GGT, and Prolactin. Hemoglobin was slightly high 166g/L the high range is 165g/L. ALP was normal at 77U/L however, AST was slightly elevated at 49U/L and ALT and GGT where almost double at the high range at 108 U/L and 105 U/L respectively. Prolactin was also double the high range at 29.8 ug/L.

I am a 23 male. 2.5 months ago I came off of anabolic steroids cycle which I was using for ~15months. I used Testosterone Enanthate, Nanadrolone (NPP), Boldenone, Oxandrolone, HCG and Trenbolone acetate. I also took an estrogen antagonist, aeromedix (Temoxifin) as an anti-estrogen. Ok before you jump to conclusion and blame my elevated liver enzyme values on steroid abuse let me explain that injectable testosterone and nandrolone are amongst the safest anabolic drugs when it comes to liver specially nandrolone. This leaves oxandolone and Aromidex. I have used oxandrolone number of time and yes my liver had been elevated but slightly and it returned to normal couple of week after I stop using it. Aeromedix has been associated with nasty liver problems in the past which I was not aware of it since now. I used it for more than 9 months. I have no data on HCG, so I can only speculate that it is not as detrimental to liver as Aeromedix since pregnant female exert HCG in their urine at ridiculous amount. But seeing that millions of female are treated for breast cancer with Aeromedix and are on the drug for longer period than I have been, I don’t think the associated elevated liver values with Aeromedix is of a concern (I maybe wrong).

Also I can not explain the elevated prolactin level. However I have a hypothesis about the AST and ALT. I took the test 2 months after anabolic steroid discontinuation. I did not work out or eat properly since I was very busy at school and exams. I believe the combination of muscle catabolism and discontinuation of anabolic agent along with bad diet and stress from school has resulted in break down of my muscle tissue resulting in increase in AST and ALT since these chemical are also released from the muscle as result of catabolism. But this does not explain why my GGT is high! Also increase in total bilirubin is result of steroid induced liver problems. My total bilirubin is very low! Also I was on medication minocycline for the whole time. Maybe that minocycline contributed? Also I have experience dry itchy skin ever since, maybe this is an indication of a liver problem. I used couple application of Hydrocortisone containing cream when the doctor misdiagnosed me with yeast infection. I discontinued it when I notice multiple severe sharp pain from my abdominal area, NOT near my liver, in the middle a little lower than the stomach. I still have the pains but it is a lot better now. I recently noticed sharp pain in my upper chest both on right and left site, which is why I took the test for cholesterol to see if I was at risk for cardiovascular disease.

I also heard that high consumption of fast foods leads to increase in liver enzymes. I have been eating them in the past month since I did not have time to prepare food. To which extent this is true I don’t know, I have yet to see a scientific research that show to which extent fast foods can have an effect on the liver values.

Also I took some glutamine the night before the test maybe that had some effect on the test results?

Anyways, if anyone knows of a case where ALP has not been elevated but ALT and GGT were double the normal range and AST was slightly elevated along with doubling of prolactin please let me know I appreciate it. Tomorrow I am taking another exam to measure the liver enzyme mentioned above plus LDH and CPK.

It is sad since most of the doctors that I know of are very incompetent or simple do not want to help, they simply dismiss my problem by just adding another drug to the list or they don’t want help because I used anabolic agents. I find it funny that my doctor didn’t know what prolactin was.

Thanks
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bazn

New User, Becoming EHEALTHy
Joined: 02 Jun 2007
Posts: 13

Posted: 06-03-07 10:10am

i'm afraid i don't know ebough about steroid use to help you on the cause of your liver test results (however i can read it up!)

what i can tell you though is that it is possible (and common) to get raised ALT/AST with a normal ALP.

the reason is that AST and ALT are liver enzymes, whereas ALP comes from the biliary tree (bile ducts). therefore if something is affecting your liver but not your biliary tree, then your liver enzyme results might be high, but the ALP may remain normal.

of course, some things affect both as they are structurally and funtionally related - and this would result in raised ALP as well as AST/ALT.
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