Joined: 11 May 2007 Posts: 1 Location: Leicester, UK
Did My Mum Have Lupus? Posted: 05-11-07 05:41am
My late mother had a question mark over
her diagnois of SLE, she was hospitalised
for several weeks and there are so many
unanswered questions as to whether she did
have this disease. All medical reports say
SLE ? I have received my mothers medical
records because my twin sister has medical
problems that the hospital cant get to the
bottom off (she has one or two autoimmune
probs already). I have listed below some
blood test results of my mothers and some
comments, if anybody can give me their
opinion if she did have SLE.
(From Heamatologist) This lady has
profound neutropenia secondary to
peripheral consumption. This is probably
an autoimmune based probelms and connected
to the likely hood of a MCTD.
Investigations:
INR, U's & E's, calcium, B12, folate
are normal, except ferritin is slightly
high at 158. White cell blood count low
at 1.2, neutrophilis low at 0.17,
heamoglobin 10.4, CRP of 104, albumen is
low at 28. Blood culture, urine culture
and sputum culture are negative.
Rheumatoid factor is positive at 138, DNA
positive at 1:12000 igC. Hep 2000 cells
(ANA) pistive homogenous pattern. DNA
binding antibodies slightly raised at 44.
ENA negative,
She also had test results from National
Blood Service in Bristol. Query
autoimmune neutropenia (neutrophil count
0.8 X 10 9/L.
Granulocyte Immunology results
These results suggest the presence of
granulocyte-reactive antibdoes in this
patiient. These antibodies reacted
indeptendantly of HNA-1, -2 & -3 and
HLA class I antigens and could not be
charaterized futher.
Can anybody tell me what all these tests
mean.
She had suffered from Rhuematoid Arthritis
for approx 40 years and doctors then
confirmed that there is very little in the
way of clinical features of a
rheumatological illness. We never
received a diagnosis of what she died of
(She suffered a stroke prior to this)
doctors told us there was numerous things
going on, suffered dementia, wasting also.
Death certificate states brain disease.
